Methods of treatment for failure to thrive
OwnerMelinda J. ELLIOTTinventor
Life of this patent
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Abstract
Provided herein are compositions and methods useful for improving or increasing weight gain or growth velocity in a subject, e.g., an infant having or suspected of having failure to thrive. In some aspects, the methods are or include administering a human milk cream composition to increase or improve growth velocity or weight gain.
Claims33
A method of treating failure to thrive in a subject, the method comprising administering to a subject in need thereof a human milk cream composition, wherein the human milk cream composition comprises from 20% to 30% human milk fat and from 2.0 kcal/mL to 3.0 kcal/mL.
The method of any of claims of 1-25, wherein the human milk cream composition comprises about 25% human milk fat and 2.5 kcal/mL to 2.7 kcal/mL.
A use of a human milk cream composition for treating failure to thrive in a subject in need thereof, wherein the human milk cream composition comprises from 20% to 30% human milk fat and from 2.0 to 3.0 kcal/mL.
Human milk cream composition for use in the manufacture of a medicament for the treatment of failure to thrive in a subject in need thereof, wherein the human milk cream composition comprises from 20% to 30% human milk fat and from 2.0 to 3.0 kcal/mL.
A method for inducing weight gain in a subject in need thereof, wherein the subject's weight for age or weight for length/height has fallen by two major percentiles since birth, the method comprising enterally or orally administering to the subject in need thereof a human milk cream composition comprising from 20% and 30% human milk fat and from 2.0 and 3.0 kcal/mL:
- wherein the subject is less than 2 years old, was at least 34 weeks gestational age at birth, and is breastfed or exclusively breastfed,
- wherein the human milk cream composition is administered at least once daily for a period of time sufficient for the subject's weight for age or weight for length/height to increase by two major percentiles,
- wherein the major percentiles are 95%, 90%, 75%, 50%, 25%, 10%, and 5%.
A method for inducing weight gain in a subject in need thereof, wherein the subject's weight for age, weight for length/height, or body mass index for age is below the tenth percentile, the method comprising enterally or orally administering to the subject in need thereof a human milk cream composition comprising from 20% and 30% human milk fat and from 2.0 and 3.0 kcal/mL:
- wherein the subject is less than 2 years old, was at least 34 weeks gestational age at birth, and is breastfed or exclusively breastfed,
- wherein the human milk cream composition is administered at least once daily for a period of time sufficient for the subject's weight for age, weight for length/height, or body mass index for age to increase to at least the tenth percentile.
Dependencies are inferred from the claim text.