Mpla compositions and methods of use
AssigneeRevelation Biosciences, Inc.
InventorsJames M. Rolke, Jackson R. Stephens, Joseph M. Ninosky
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Abstract
Disclosed are pharmaceutical compositions of monophosphoryl lipid A (MPLA) like compounds, as well as methods of preparing such pharmaceutical compositions, and method of use for such compositions in treating allergic disease.
Claims63
A pharmaceutical composition comprising a colloidal formulation of one or more monophosphoryl lipid A (MPLA) like compounds.
The pharmaceutical composition of any one of claims 1-33, wherein the composition further comprises one or more surfactants selected from poloxamer 407, poloxamer 181, dodecyltrimethylammonium bromide (DTAB), n-dodecyl octa (ethylene oxide) (C12E8), n-dodecyl tetra (ethylene oxide) (C12E4), dioctanoyl phosphatidylcholine (C8-lecithin), Polyoxyl 35 castor oil, Cremophor EL (CrEL), Octaethylene glycol monododecyl ether (C12E8), hexadecyltrimethylammonium bromide (CTAB), polypropylene oxide (PPO), polyethylene oxide (PEO), PEO-poly(D,L-lactic acid-co-caprolactone) (PEO-PDLLA), sodium dodecyl sulfate (SDS), and any combination thereof.
Dependencies are inferred from the claim text.