Novel use of pyrrolopyridine derivatives for preventing or treating inflammatory diseases

A method of reducing pro-inflammatory cytokines in a patient in need thereof, the method comprising administering to the patient a compound represented by Chemical Formula 1:

• or an isomer, pharmaceutically acceptable salt, or pharmaceutical composition thereof, wherein:
• R1 is C1-C3 alkoxy;
• R2 and R3 are each independently hydrogen, straight chain or branched chain C1-C10 alkyl, or C3-C6 cycloalkyl;
• and
• R4 is haloalkyl.

A method of increasing differentiation of regulatory T cells (Treg) in a patient in need thereof, the method comprising administering to the patient a compound represented by Chemical Formula 1:

• or an isomer, pharmaceutically acceptable salt, or pharmaceutical composition thereof, wherein:
• R1 is C1-C3 alkoxy;
• R2 and R3 are each independently hydrogen, straight chain or branched chain C1-C10 alkyl, or C3-C6 cycloalkyl;
• and
• R4 is haloalkyl.

A method of decreasing pro-inflammatory T cells in a patient in need thereof, the method comprising administering to the patient a compound represented by Chemical Formula 1:

• or an isomer, pharmaceutically acceptable salt, or pharmaceutical composition thereof, wherein:
• R1 is C1-C3 alkoxy;
• R2 and R3 are each independently hydrogen, straight chain or branched chain C1-C10 alkyl, or C3-C6 cycloalkyl;
• and
• R4 is haloalkyl.