Methods and compositions for treating excessive sleepiness
AssigneeAxsome Malta Ltd.
InventorsLawrence Patrick Carter, Yuan Lu, Katayoun Zomorodi
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Abstract
The present invention relates to carbamoyl phenylalaninol compounds and methods of using the same to treat disorders. The invention further relates to the development of methods for treating excessive sleepiness in a subject, e.g., due to narcolepsy or obstructive sleep apnea, with the surprising outcome that “normal” levels of wakefulness are achieved based on standard objective and subjective sleepiness tests.
Claims30
A method for treating excessive daytime sleepiness in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of (R)-2-amino-3-phenylpropyl carbamate (APC) or a pharmaceutically acceptable salt thereof, wherein the APC or a pharmaceutically acceptable salt thereof is administered to the subject within 3 hours of the subject waking.
A method for minimizing insomnia while treating excessive daytime sleepiness in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of (R)-2-amino-3-phenylpropyl carbamate (APC) or a pharmaceutically acceptable salt thereof, wherein the APC or a pharmaceutically acceptable salt thereof is administered to the subject within 3 hours of the subject waking.
Dependencies are inferred from the claim text.