Compositions
AssigneeVitux Group AS
InventorsMorten J DILLE, Tuna BAYDIN, Magnus HATTREM, Kurt Ingar DRAGET
Life of this patent
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Abstract
The invention relates to compositions for oral administration which are provided in the form of gelled oil-in-water emulsions, to methods for their preparation and to their use as pharmaceuticals and nutraceuticals. In particular, it relates to orally administrable. gelled oil-in-water emulsions which are self-supporting. viscoelastic solids having a gelled aqueous phase comprising a gelling agent which is agar, and wherein said emulsion is stabilised by a surfactant which is a plant-based protein. plant-based polysaccharide or derivative thereof.
Claims25
An orally administrable, gelled oil-in-water emulsion which is a self-supporting, viscoelastic solid having a gelled aqueous phase comprising a gelling agent which is agar, and wherein said emulsion is stabilised by a surfactant which is a plant-based protein, plant-based polysaccharide or derivative thereof.
An orally administrable, gelled oil-in-water emulsion as claimed in any one of the preceding claims which contains agar at concentration from about 0.1 to about 5 wt. % based on the total weight of the emulsion.
An orally administrable, gelled oil-in-water emulsion as claimed in any one of the preceding claims which further contains glycerol.
An orally administrable, gelled oil-in-water emulsion as claimed in any one of the preceding claims, wherein said aqueous phase constitutes from 50 to 95 wt. %, preferably from 55 to 90 wt. %, for example from 60 to 85 wt. %, from 70 to 85 wt. %, or from 75 to 80 wt. % of the emulsion.
An orally administrable, gelled oil-in-water emulsion as claimed in any one of the preceding claims, wherein the aqueous phase further comprises one or more bulking agents, for example sugar alcohols or sugars.
An orally administrable, gelled oil-in-water emulsion as claimed in any one of the preceding claims having an oil phase which comprises one or more physiologically tolerable lipids derived from rapeseed oil, sunflower oil, corn oil, olive oil, sesame oil, palm kernel oil, coconut oil, a nut oil, algae oil or hemp oil.
An orally administrable, gelled oil-in-water emulsion as claimed in any one of the preceding claims having an oil phase which constitutes from 5 to 50 wt. %, preferably from 10 to 45 wt. %, for example from 15 to 40 wt. %, from 15 to 30 wt. % or from 20 to 25 wt. %. of the emulsion.
An orally administrable, gelled oil-in-water emulsion as claimed in any one of the preceding claims which further comprises at least one pharmaceutically active agent.
An orally administrable, gelled oil-in-water emulsion as claimed in any one of the preceding claims which further comprises at least one nutraceutically active agent.
An orally administrable, gelled oil-in-water emulsion as claimed in any one of the preceding claims which is provided in unit dose form.
Dependencies are inferred from the claim text.