Interbody fusion devices and related methods of manufacture

An interbody fusion device comprising top and bottom endplates, first and second lateral sides, anterior end, posterior end, and a body;

• said body positioned between said top and bottom endplates;
• each of said top and bottom endplates are configured to interface or engage with bone when said interbody fusion device is positioned between adjacent vertebra of a spine;
• said body includes a body cavity;
• one or both of said first and second lateral side includes one or more lateral openings that terminate in said body cavity;
• said posterior end includes a first posterior opening that terminates in said body cavity;
• said top endplate is formed of a top lattice structure;
• said bottom endplate is formed of a bottom lattice structure;
• said top lattice structure on said top endplate forming a plurality of top openings that terminate in said body cavity;
• said bottom lattice structure on said bottom endplate forming a plurality of bottom openings that terminate in said body cavity;
• said top frame of said top endplate includes a top aperture region that is positioned adjacent to at least a portion of said top lattice structure;
• at least a portion of said top aperture region is positioned between said top lattice structure and a peripheral edge of said top endplate;
• said top aperture region includes a) a plurality of top micro-apertures, and wherein said plurality of top micro-apertures has an average size that is smaller in cross-sectional area than a cross-sectional area of said plurality of top openings of said plurality of top openings, and/or b) a plurality of top macro-apertures, and wherein said plurality of top macro-apertures has an average size that is smaller in cross-sectional area than a cross-sectional area of said plurality of top openings of said plurality of top openings.