Transcutaneous analyte sensors and monitors, calibration thereof, and associated methods
AssigneeDexCom, Inc.
InventorsArturo Garcia, Peter C Simpson, Apurv U Kamath, Naresh C. Bhavaraju, Stephen J. Vanslyke
Life of this patent
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Abstract
Systems and methods are provided to calibrate an analyte concentration sensor within a biological system, generally using only a signal from the analyte concentration sensor. For example, at a steady state, the analyte concentration value within the biological system is known, and the same may provide a source for calibration. Similar techniques may be employed with slow-moving averages. Variations are disclosed.
Claims20
(canceled)
A method of compensating for drift in a glucose sensor within a biological system using only a signal from the glucose sensor, the method comprising:
- measuring glucose concentration values using an indwelling glucose sensor;
- determining a first slow-moving average of the measured glucose concentration values over a first period of time, and basing a first apparent sensitivity of the indwelling glucose sensor based at least in part on the first slow-moving average;
- determining, after determining the first slow-moving average, a second slow-moving average of the measured glucose concentration values over a second period of time, and basing a second apparent sensitivity of the indwelling glucose sensor based at least in part on the second slow moving average;
- determining a difference between the first apparent sensitivity and the second apparent sensitivity fails to meet a predetermined criteria;
- and
- performing a recalibration routine based on determining the difference fails to meet the predetermined criteria.
A glucose sensor system, comprising:
- a glucose sensor;
- and
- a processor programmed to perform operations comprising:
- measuring glucose concentration values using the glucose sensor;
- determining a first slow-moving average of the measured glucose concentration values over a first period of time, and basing a first apparent sensitivity of the glucose sensor based at least in part on the first slow-moving average;
- determining, after determining the first slow-moving average, a second slow-moving average of the measured glucose concentration values over a second period of time, and basing a second apparent sensitivity of the glucose sensor based at least in part on the second slow moving average;
- determining a difference between the first apparent sensitivity and the second apparent sensitivity fails to meet a predetermined criteria;
- and
- performing a recalibration routine based on determining the difference fails to meet the predetermined criteria.
A processor for a glucose system, the processor being programmed to perform operations comprising:
- measuring glucose concentration values using a glucose sensor;
- determining a first slow-moving average of the measured glucose concentration values over a first period of time, and basing a first apparent sensitivity of the glucose sensor based at least in part on the first slow-moving average;
- determining, after determining the first slow-moving average, a second slow-moving average of the measured glucose concentration values over a second period of time, and basing a second apparent sensitivity of the glucose sensor based at least in part on the second slow moving average;
- determining a difference between the first apparent sensitivity and the second apparent sensitivity fails to meet a predetermined criteria;
- and
- performing a recalibration routine based on determining the difference fails to meet the predetermined criteria.
Dependencies are inferred from the claim text.