System and solution for improved whole blood storage
AssigneeHemerus Medical, LLC
InventorsJohn HESS, Majid ZIA
Life of this patent
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Abstract
A whole blood storage system that includes whole blood leukoreduction with pH optimization for improved RBC storage. Such a system can provide leukoreduced whole blood for field medical use, but would preserve the RBCs and most plasma coagulation activity for at least about 2 weeks, or about 3 weeks, or about 4 weeks, or about 5 weeks or about 6 weeks so that the units would not go to waste.
Claims20
A whole-blood storage system that includes whole blood leukoreduction filter with pH optimization for improved red blood cell (RBC) storage, comprising:
- a first additive;
- and
- a second additive;
- wherein
- upon the first additive and the second additive being combined with whole blood the coagulation capability of the whole blood is maintained for at least about 3 weeks or at least about 4 weeks or at least about 5 weeks after combination.
A whole-blood storage system that includes a whole blood leukoreduction filter with pH optimization for improved red blood cell (RBC) storage, comprising:
- a first additive;
- and
- a second additive;
- upon the first additive and the second additive being combined with whole blood, the whole blood can be preserved for at least about 2 weeks, or about 3 weeks, or about 4 weeks, or about 5 weeks after combination and red blood cells for at least about 2 weeks, or about 3 weeks, or about 4 weeks, or about 5 weeks or about 6 weeks after combination.
A method of storing whole-blood with a whole-blood storage system storage system that includes whole blood leukoreduction with pH optimization for improved red blood cell (RBC) storage, the storage system comprising:
- a first bag containing a first additive;
- and
- a second bag containing a second additive;
- the method comprising:
- adding whole blood to be collected into the first bag,
- before or after adding the whole blood into the first bag,
- transferring the second additive from the second bag to the first bag;
- wherein the additives combine to preserve the RBCs and most coagulation capability for at least about 3 weeks or at least about 4 weeks or at least about 5 weeks;
- and
- storing the whole blood for a period of up to about 2 weeks, or about 3 weeks, or about 4 weeks, or about 5 weeks or about 6 weeks.
A method of storing red blood cells separated from whole blood, with a storage system storage system that includes whole blood leukoreduction with pH optimization for improved red blood cell (RBC) storage, the storage system comprising:
- a first bag containing a first additive;
- and
- a second bag containing a second additive;
- the method comprising:
- adding whole blood into the first additive bag,
- before or after adding the whole blood to be stored into the first bag, transferring the second additive from the second bag to the first bag;
- wherein the additives combine to preserve the RBCs and most coagulation capability for at least about 3 weeks or at least about 4 weeks or at least about 5 weeks;
- the method further comprising separating the RBCs from the whole blood, and storing the RBCs for a period of up to about 2 weeks, or about 3 weeks, or about 4 weeks, or about 5 weeks, or about 6 weeks after separating the RBCs from the whole blood.
Dependencies are inferred from the claim text.