Switchable ion guide
AssigneeThermo Fisher Scientific (Bremen) GmbH
InventorsHenning WEHRS, Johannes SCHWIETERS, Gerhard JUNG
Life of this patent
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Abstract
An ion optical arrangement (1) for use in a mass spectrometer comprises a collision cell defining an ion optical axis along which ions may pass, electrodes comprising a set of parallel poles (11A, 11B, 11C) arranged in the collision cell, and a voltage source for providing voltages to the electrodes to produce electric fields. The ion optical arrangement is arranged for switching between a first operation mode in which the collision cell is pressurized and a second operation mode in which the collision cell is substantially evacuated. The ion optical arrangement is further arranged for producing a radio frequency electric focusing field in the first operation mode and a static electric focusing field in the second operation mode.
Claims21
1-23. (canceled)
An ion optical arrangement for use in a mass spectrometer comprising:
- a collision cell defining an ion optical axis along which ions may pass;
- electrodes comprising a set of parallel poles arranged in the collision cell;
- a voltage source for providing voltages to the electrodes to produce electric fields;
- wherein the ion optical arrangement is arranged for switching between a first operation mode in which the collision cell is pressurized and a second operation mode in which the collision cell is substantially evacuated, and
- wherein the ion optical arrangement is further arranged for producing a radio frequency electric focusing field with the electrodes in the first operation mode and a static electric focusing field in the second operation mode.
The ion optical arrangement according to claim 25, wherein the direct current voltages supplied to a first and a third section of a pole are substantially equal, while the direct current voltage supplied to a second section of a pole is a different voltage.
A method of filtering ions using a collision cell, the ions following a trajectory through the collision cell, the method comprising:
- switching between a first operation mode in which the collision cell is pressurized and a second operation mode in which the collision cell is substantially evacuated;
- and
- producing in the collision cell a radio frequency electric field focusing field in the first operation mode and a static electric focusing field in the second operation mode, wherein the radio frequency electric field focusing field is provided by electrodes comprising a set of parallel poles arranged in the collision cell.
Dependencies are inferred from the claim text.