Automated calibration method and system for a diagnostic analyzer

A system for calibrating a diagnostic analyzer having one or more parameters, the system comprising:

• at least one computer accessible-storage device configured to store instructions;
• and
• at least one processor communicatively connected to the at least one computer accessible storage device and configured to execute the instructions to:
• receive first diagnostic results from the diagnostic analyzer;
• determine whether the first diagnostic results exceed a predetermined threshold from a first diagnostic target;
• adjust, in a case where the first diagnostic results exceed the predetermined threshold, one or more laser settings for the diagnostic analyzer;
• receive a plurality of patient samples for interrogation by the diagnostic analyzer;
• determine weighted averaged diagnostic results associated with the plurality of patient samples interrogated by the diagnostic analyzer using the adjusted one or more laser settings and one or more calibration factors corresponding to the one or more parameters for the diagnostic analyzer;
• determine whether the weighted averaged diagnostic results fall outside of a permissible range;
• and
• in a case where the weighted averaged diagnostic results fall outside of the permissible range:
• determine one or more multiplying factors for the one or more calibration factors that permit the weighted averaged diagnostic results to fall within the permissible range;
• and
• calibrate the diagnostic analyzer by adjusting the one or more calibration factors corresponding to the one or more parameters of the diagnostic analyzer based at least in part on the one or more multiplying factors.

A non-transitory computer readable storage medium configured to store a program, executed by a computer, for a system for calibrating a diagnostic analyzer having one or more parameters, the program including instructions for:

• receiving first diagnostic results from the diagnostic analyzer;
• determining whether the first diagnostic results exceed a predetermined threshold from a first diagnostic target;
• adjusting, in a case where the first diagnostic results exceed the predetermined threshold, one or more laser settings for the diagnostic analyzer;
• receiving a plurality of patient samples for interrogation by the diagnostic analyzer;
• determining weighted averaged diagnostic results associated with the plurality of patient samples interrogated by the diagnostic analyzer using the adjusted one or more laser settings and one or more calibration factors corresponding to the one or more parameters for the diagnostic analyzer;
• determining whether the weighted averaged diagnostic results fall outside of a permissible range;
• and
• in a case where the weighted averaged diagnostic results fall outside of the permissible range:
• determining one or more multiplying factors for the one or more calibration factors that permit the weighted averaged diagnostic results to fall within the permissible range;
• and
• calibrating the diagnostic analyzer by adjusting the one or more calibration factors corresponding to the one or more parameters of the diagnostic analyzer based at least in part on the one or more multiplying factors.