Actrii proteins and uses thereof
AssigneeAcceleron Pharma Inc.
InventorsGang Li, Ravindra Kumar
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Abstract
In some aspects, the disclosure relates to compositions and methods comprising ActRII polypeptides to treat, prevent, or reduce the progression rate and/or severity of hyperglycemia, particularly treating, preventing or reducing the progression rate and/or severity of one or more hyperglycemia-associated complications.
Claims29
method of treating hyperglycemia associated with pulmonary hypertension, comprising administering to a patient in need thereof an effective amount of an ActRII polypeptide comprising an amino acid sequence that is at least 85% identical to an amino acid sequence that begins at any one of amino acids 110-135 of SEQ ID NO:
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Dependencies are inferred from the claim text.