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US 2024/0174688 A1Published application
Compositions and methods of modulating short-chain dehydrogenase activity
OwnerSanford Markowitz, Joseph Ready +5inventors
InventorsSanford Markowitz, Joseph Ready, Yongyou Zhang, Monika Antczak, James K.V. Willson, Bruce Posner, William Greenlee
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Abstract
Compounds and methods of modulating 15-PGDH activity, modulating tissue prostaglandin levels, treating disease, diseases disorders, or conditions in which it is desired to modulate 15-PGDH activity and/or prostaglandin levels include 15-PGDH inhibitors described herein.
Claims12
A compound having formula selected from the group consisting of:
- or a pharmaceutically acceptable salt thereof.
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Dependencies are inferred from the claim text.