Small Molecule Compound
OwnerLi Xing, Guanqun Li +7inventors
InventorsLi Xing, Guanqun Li, Xiaolei Wang, Yuting Cai, Xiang Jiang, Xiang Pan, Wenhao Zhu, Yang Wang, Zengquan Wang
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OwnerLi Xing, Guanqun Li +7inventors
InventorsLi Xing, Guanqun Li, Xiaolei Wang, Yuting Cai, Xiang Jiang, Xiang Pan, Wenhao Zhu, Yang Wang, Zengquan Wang
Estimating the term…
Provided is a small molecule compound, which is characterized in having the structure represented by the following molecular formula: (I), wherein X1 and X2 are selected from carbon or nitrogen; G1 is a carbocyclic ring or heterocyclic ring having aromaticity; any one or more hydrogen atoms on the ring of G1 are substituted by R1; and R1 is selected from nitrogen-containing groups. The small molecule compound of the present invention can be used as a highly effective and specific JAK kinase inhibitor, specifically a Tyk2 inhibitor; and/or a JAK1 inhibitor, and/or a JAK1/Tyk2 or Tyk2/JAK1, Tyk2/Jak2 dual inhibitor.
A small molecule compound, which is characterized by being a compound represented by the following structural formula or stereoisomer, geometric isomer, tautomer, racemate, hydrate, solvate, a metabolite and a pharmaceutically acceptable salt or a prodrug thereof:
Dependencies are inferred from the claim text.