Kinase modulators and methods of use thereof

A method of treatment of a patient suffering from a neurological condition, wherein the method comprises administering a therapeutically effective amount of compound of Formula (I):

• and pharmaceutically acceptable salts thereof,
• wherein:
• G1 is CF3, CHF2, CH2F, halogen or cyclopropyl, ethyl, isopropyl;
• G2 is H, substituted or unsubstituted C1-C6-alkyl, C3-C6-cycloalkyl, C1-C6 haloalkyl, C3-C6-halocycloalkyl, C3-C6-heterocycloalkyl, heteroaryl, —CH2-cycloalkyl, —CF2-cycloalkyl, —CH(CH3)-cycloalkyl, —CH2-aryl, —CH2-heterocycloalkyl, —CH2-heteroaryl, —CF2-aryl, and —CH(—CH3)-aryl;
• A and B are independently selected from 5 or 6 membered cycloalkyl or aryl rings comprising one or more heteroatoms and one or more substitutions;
• wherein both A and B comprise, cumulatively, at least two (2) nitrogen heteroatoms;
• wherein A and B are fused at 2 positions;
• wherein the one or more substitutions on the A and B rings are independently selected from:
• H, halo, C1-C6-alkyl, branched alkyl, haloalkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, alkoxy, cycloalkoxy, haloalkoxy, alkoxyalkoxy, cyano, —CH2-cycloalkyl, —CF2-cycloalky, —(CH2)0-2C(CH3)CN, —(CH2)0-4—CN, —(CH2)0-4SO2R′, —CH(CH3)-cycloalkyl, —CH2-aryl, —CF2-aryl, —CH(—CH3)-aryl, —C(═O)-alkyl, —C(═O)cycloalkyl, —C(═O)—NR′R″, —C(═O)—NH-alkyl, —C(═O)NH2, hydroxy, —COOH (and ester thereof), alkylsulfonyl, cycloalkylsulfonyl, arylsulfonyl, —S(═O)2—NR′R″, —NH, —NR′R″, —NR′—S(═O)2R″, cyanoalkyl, haloalkyl, substituted or unsubstituted alkylsulfonyl, arylsulfonyl, —C(═O)-morpholine, —C(═O)-heterocycles, —C(H)0-1(—CH3)1-2—OH, —CH2—C(═O)—NH2;
• 3-6 membered heterocycle, any of which may have one or more substituents, wherein the 3-6 membered heterocycle comprises at least one heteroatom independently selected from O, S, and N;
• wherein R′ and R″ are independently selected from a group consisting of H, alkyl, substituted or unsubstituted aryl, and heterocycles.