Metal salts and uses thereof
AssigneeInspirna, Inc.
InventorsStephen WALD, Eduardo J. MARTINEZ, Samuel STRATFORD, Amanda BUIST, Joseph BENSON, Jonathan LOUGHREY
Life of this patent
Estimating the term…
Abstract
The present invention relates to metal salts of 2-[3-[(3R)-3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]butoxy]phenyl]acetic acid which exhibit improved physical properties and stability. The invention also relates to pharmaceutical compositions including an effective amount of the metal salts, as well as methods of treating cancer including administration of a pharmaceutical composition including a salt of the invention to a subject in need thereof.
Claims19
A method of cancer in a subject in need thereof, the method comprising administering to the subject an effective amount of a zinc salt of 2-[3-[(3R)-3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-(2,2-diphenylethyl)amino]butoxy] phenyl]acetic acid (Compound 1), wherein the zinc salt is a 2:1 (Compound 1:zinc) salt, and wherein the cancer is lung cancer or endometrial cancer.
Dependencies are inferred from the claim text.