Stable liquid thrombin compositions
AssigneeOmrix Biopharmaceuticals Ltd.
InventorsErez ILAN, Omri FAINGOLD, Sivan DORON
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Abstract
The present invention provides methods for large scale preparation of sterile stable liquid thrombin composition comprised of glycerol; stable liquid thrombin compositions; and hemostatic composition and kits. The present invention further provides hemostatic compositions comprised of liquid thrombin, glycerol and gelatin. Further provided herein is a method for the large-scale production of a sterile liquid thrombin composition comprised of glycerol.
Claims5
A hemostatic composition comprising thrombin, gelatin, and glycerol at a concentration range above 30% of the solids by weight.
The hemostatic composition according to claim 8, further comprising calcium.
The hemostatic composition according to claim 8, further comprising one or more excipients selected from the group consisting of sodium chloride, mannitol, albumin, and sodium acetate.
The hemostatic composition according to claim 8, comprising between about 100 and about 2,000 IU/ml of thrombin.
The hemostatic composition of claim 8, for topical use to assist in hemostasis.
Dependencies are inferred from the claim text.