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US 2024/0173377 A1Published application
Retro - inverso regulatory t cell epitopes
OwnerAnne De Groot, William Martininventors
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Abstract
The present disclosure provides retro-inverso Tregitope compounds and compositions as well as methods for their preparation and use.
Claims22
1-79. (canceled)
A composition comprising:
- a polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NOS:
- 1-29 and 42-107, and/or fragments and variants thereof, and optionally 1 to 12 additional amino acids distributed in any ratio on the N terminus and/or C-terminus of the polypeptide of SEQ ID NOS:
- 1-29 and 42-107, wherein each of the amino acids of SEQ ID NOS:
- 1-29 and 42-107, and optionally the extensions thereof, except for glycine are in the D-amino acid configuration,
- a nucleic acid encoding said polypeptide, or
- a vector comprising said nucleic acid, or
- a cell comprising said vector.
4 more elements
Dependencies are inferred from the claim text.