Nasal compositions comprising alcaftadine
AssigneeAlkem Laboratories Limited
InventorsAkhilesh SHARMA, Babasaheb AWARE, Viraj SHAH, Amol AIWALE
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Abstract
The present invention relates to a nasal pharmaceutical composition comprising alcaftadine or a pharmaceutically acceptable salt and optionally one or more pharmaceutically acceptable excipients, methods of treating allergic rhinitis, allergic rhino-conjunctivitis, or symptoms thereof (such as nasal congestion) with the nasal pharmaceutical composition, and methods of preparing it.
Claims21
A nasal pharmaceutical composition comprising alcaftadine or a pharmaceutically acceptable salt thereof and a mucoadhesive agent.
An aqueous nasal pharmaceutical composition comprising (i) about 0.1 to 1.0% w/w alcaftadine or a pharmaceutically acceptable salt thereof, (ii) about 0.01 to 1.0% w/w hydroxypropyl methyl cellulose, (iii) about 0.068 to about 6.8% w/w of sodium chloride, (iv) about 0.0019 to about 0.19% w/w monobasic sodium phosphate, (v) about 0.005 to about 0.5% w/w disodium edetate, and (vi) about 0.0025 to about 0.25% w/w benzalkonium chloride, wherein the composition has a pH of 6.3 to 7.3.
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Dependencies are inferred from the claim text.