Scaffolds For Inducing Antibody Responses Against Antigenic Sites
AssigneeEmory University
InventorsChinglai Yang, Ling Ye, Samuel Stampfer, Rui Jin
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Abstract
This disclosure relates to scaffolds for inducing antibody responses against antigenic sites. In certain embodiments, this disclosure relates to compositions and methods using a filovirus sGP as a scaffold for inducing antibody responses against antigenic sites in foreign pathogens. In certain embodiments, this disclosure relates to compositions and methods using a filovirus sGP as a scaffold for inducing antibody responses against a virus to produce a viral vaccine.
Claims16
A fusion protein comprising a heterologous sequence inserted in the middle of a filovirus secreted glycoprotein (sGP).
Dependencies are inferred from the claim text.