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US 2024/0165152 A1Published application
Compositions and methods for activating nk cells
AssigneeThe Regents of the University of California
InventorAnahid JEWETT
Life of this patent
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Abstract
The present application relates to methods of activating a NK cells in vitro, ex vivo, and/or in vivo by an osteoclast cell (OC) and/or a dendritic cell, and methods of treating disease using these activated NK cells.
Claims21
1-82. (canceled)
A method of expanding and/or activating a T cell, the method comprising:
- (a) first culturing an NK cell and an osteoclast cell (OC) in a cell culture;
- and
- (b) subsequently contacting the NK cell with the T cell,
- thereby expanding and/or activating the T cell,
- optionally wherein the T cell is a CD8+ T cell.
2 more elements
A method of activating and/or expanding a T cell, the method comprising culturing the T cell and an osteoclast cell (OC) in a cell culture.
Dependencies are inferred from the claim text.