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US 2024/0151709 A1Published application
Compositions and methods for tracing cell networks
AssigneeThe Brigham and Women S Hospital, Inc.
InventorsFrancisco J. Quintana, Michael A. Wheeler, Iain C. Clark
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Abstract
The present application relates to compositions and methods for tracing cell networks, e.g., for investigation of cell interactions in the CNS with single cell resolution.
Claims36
A recombinant rabies virus comprising:
- a polynucleotide encoding a foreign virus envelope protein;
- and
- a polynucleotide encoding:
- a fluorescent protein;
- a barcode sequence flanked by a first common sequence and a second common sequence;
- and
- a 3′ poly(A) tail,
- wherein the recombinant rabies virus does not encode a functional G protein.
5 more elements
Dependencies are inferred from the claim text.