Identification of oleanolic acid and plant extract for glucose-6-phosphate dehydrogenase-related disorders including Bag3opathy
AssigneeHong Kong Baptist University
InventorsZhaoxiang BIAN, Tao HUNG, Ling ZHAO, Lidan ZHONG, Chengyuan LIN
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Abstract
A method of treating a glucose-6-phosphate dehydrogenase deregulated disorder in a subject in need thereof, the method involving administering a therapeutically effective amount of oleanolic acid or a conjugate salt thereof or prodrug thereof to the subject. The glucose-6-phosphate dehydrogenase deregulated disorder can be BCL2 associated athanogene myofibrillar myopathy, amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, or Alzheimer disease.
Claims19
A method of treating a glucose-6-phosphate dehydrogenase (G6PD) deregulated disorder in a subject in need thereof, the method comprising administering a therapeutically effective amount of oleanolic acid, a conjugate salt thereof, or a prodrug thereof to the subject.
A method of treating BCL2 associated athanogene myofibrillar myopathy (Bag3opathy) in a subject in need thereof, the method comprising administering a therapeutically effective amount of oleanolic acid, a conjugate salt thereof, or a prodrug thereof to the subject.
Dependencies are inferred from the claim text.