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US 2024/0141430 A1Published application
Antidote-mediated reversal of extracellular aptamer staining
AssigneeDuke University
InventorsBruce Sullenger, Bethany Gray, Michael Nichols
Life of this patent
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Abstract
Provided herein are compositions and methods for sorting and/or identifying live cells. The compositions and methods provide for staining of live cells with aptamer so particular cells can be identified within or sorted from a heterogeneous population of live cells and subsequent reversal of the staining to prepare sorted and/or identified cells in their native state.
Claims10
1-24. (canceled)
An aptamer conjugate comprising a sorting aptamer, the sorting aptamer comprising a binding label complexed to a linker, the linker comprising a reporter label and/or a magnetic label.
Dependencies are inferred from the claim text.