Composition for predicting or diagnosing early-stage diffuse gastric cancer, comprising preparation for measuring level of pepsinogen ii
AssigneeSeoul National University Hospital
InventorNayoung Kim
Life of this patent
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AssigneeSeoul National University Hospital
InventorNayoung Kim
Estimating the term…
The composition, kit and information provision method, according to an aspect of the present invention, may predict or diagnose early-stage diffuse-type gastric cancer with high sensitivity and specificity when the level of serum pepsinogen II is equal to or greater than 20 μg/L, and further, may classify the risk of early-stage diffuse-type gastric cancer in a subject on the basis of whether the level of serum pepsinogen II is equal to or greater than 20 μg/L and whether the status of Helicobacter pylori (HP) is positive, and thus, the composition, comprising a preparation capable of measuring the level of serum pepsinogen II, or, along with said preparation, a preparation capable of detecting the status of HP, the kit and the information provision method using same have an excellent effect of being capable of being usefully employed as non-invasive means which may be carried out prior to an endoscopy.
A method for predicting or diagnosing early-stage diffuse-type gastric cancer, comprising measuring a level of pepsinogen II (PGII) in a sample of a subject under age of 40.
A method for predicting or diagnosing early-stage diffuse-type gastric cancer, comprising measuring a level of pepsinogen II (PGII) in serum of a female under age of 40 and detecting Helicobacter pylori.
A kit for predicting or diagnosing early-stage diffuse-type gastric cancer, comprising a composition comprising measuring a level of pepsinogen II (PGII) in a sample of a subject under age of 40.
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Dependencies are inferred from the claim text.