Fused heterobicyclic antiviral agents

A compound represented by Formula (I):

• or a pharmaceutically acceptable salt thereof, wherein:
• Q1, Q2, Q3, an Q4 are each independently selected from hydrogen, optionally substituted —C1-C6 alkyl, optionally substituted —C2-C6 alkenyl, optionally substituted —C1-C6 alkoxy, optionally substituted —C3-C8 cycloalkyl, optionally substituted —C3-C8 cycloalkenyl, optionally substituted 3- to 8-membered heterocycloalkyl, optionally substituted aryl, and optionally substituted heteroaryl;
• alternatively, Q1 and Q2 are taken together with the atoms to which they are attached to form an optionally substituted 3-8 membered heterocyclic or carbocyclic ring containing 0, 1, 2, or 3 double bonds;
• alternatively, Q2 and Q3 are taken together with the carbon atom to which they are attached to form an optionally substituted 3-8 membered heterocyclic or carbocyclic ring containing 0, 1, 2, or 3 double bonds;
• L is CR14 or N;
• Z1, Z3, and Z4 are each independently selected from:
• 1) hydrogen;
• 2) halogen;
• 3) —NO2;
• 4) Cyano;
• 5) Optionally substituted —C1-C8 alkyl;
• 6) Optionally substituted —C2-C8 alkenyl;
• 7) Optionally substituted —C2-C8 alkynyl;
• 8) Optionally substituted —C3-C5 cycloalkyl;
• 9) Optionally substituted 3- to 12-membered heterocycloalkyl;
• 10) Optionally substituted aryl;
• 11) Optionally substituted arylalkyl;
• 12) Optionally substituted heteroaryl;
• 13) Optionally substituted heteroarylalkyl;
• 14) —SR11;
• 15) —S(O)2R11;
• 16) —S(O)2N(R11)(R12);
• 17) —C(O)R11;
• 18) —C(O)OR11;
• 19) —C(O)N(R11)(R12);
• 20) —C(O)N(R11)S(O)2(R12);
• 21) —N(R11)(R12);
• 22) —N(R13)C(O)N(R11)(R12);
• 23) —N(R11)C(O)(R12);
• 24) —N(R11)C(O)2(R12);
• 25) —N(R13)S(O)2N(R11)(R12);
• 26) —N(R11)S(O)2(R12);
• 27) —OR11;
• 28) —OC(O)R11;
• 29) —OC(O)OR11;
• and
• 30) —OC(O)N(R11)(R12);
• Z2 is selected from:
• 1) Optionally substituted —C3-C8 cycloalkyl;
• 2) Optionally substituted 3- to 12-membered heterocycloalkyl;
• 3) Optionally substituted aryl;
• 4) Optionally substituted arylalkyl;
• 5) Optionally substituted heteroaryl;
• and
• 6) Optionally substituted heteroarylalkyl;
• R11, R12, and R13, are each independently selected from hydrogen, optionally substituted —C1-C8 alkyl, optionally substituted —C2-C8 alkenyl, optionally substituted —C3-C8 cycloalkyl, optionally substituted 3- to 8-membered heterocycloalkyl, optionally substituted aryl, optionally substituted arylalkyl, optionally substituted heteroarylalkyl, and optionally substituted heteroaryl;
• alternatively, R11 and R12 are taken together with the nitrogen atom to which they attached to form an optionally substituted 3-8 membered heterocyclic containing 0, 1, 2, or 3 double bonds;
• and R14 is hydrogen, optionally substituted —C1-C6 alkyl, optionally substituted —C2-C6 alkenyl, optionally substituted —C2-C6 alkynyl, or optionally substituted —C1-C6 alkoxy.