Compositions comprising animal hemoglobin
AssigneeEvelo Biosciences, Inc.
InventorAlexander Bank
Life of this patent
Estimating the term…
Abstract
Methods and compositions related to pharmaceutical agents, pharmaceutical compositions, and solid dosage forms comprising animal hemoglobin and bacteria or agents of bacterial origin are provided herein.
Claims67
A bacterial composition comprising:
- (a) bacteria and/or microbial extracellular vesicles (mEVs);
- and
- (b) animal hemoglobin.
The bacterial composition of any one of claims 16 to 39, wherein the mEVs are lyophilized mEVs.
A solid dosage form comprising:
- (i) a pharmaceutical agent, wherein the pharmaceutical agent comprises
- (a) bacteria and/or microbial extracellular vesicles (mEVs);
- and
- (b) animal hemoglobin;
- and
- (ii) at least one diluent, at least one lubricant, at least one glidant, and/or at least one disintegration agent.
A solid dosage form comprising:
- (i) a pharmaceutical agent, wherein the pharmaceutical agent comprises
- (a) bacteria and/or microbial extracellular vesicles (mEVs);
- and
- (b) animal hemoglobin;
- and
- (ii) at least one diluent, at least one lubricant, and/or at least one glidant.
A method of preparing a solid dosage form, the method comprising:
- (A) combining into a pharmaceutical composition:
- (i) a pharmaceutical agent, wherein the pharmaceutical agent comprises
- (a) bacteria and/or microbial extracellular vesicles (mEVs);
- and
- (b) animal hemoglobin;
- and
- (ii) at least one diluent, at least one lubricant, at least one glidant, and/or at least one disintegration agent.
- (B) compressing the pharmaceutical composition into a solid dosage form.
A method of preparing a solid dosage form, the method comprising combining into a pharmaceutical composition:
- (i) a pharmaceutical agent, wherein the pharmaceutical agent comprises
- (a) bacteria and/or microbial extracellular vesicles (mEVs);
- and
- (b) animal hemoglobin;
- and
- (ii) at least one diluent, at least one lubricant, and/or at least one glidant.
A method of testing a pharmaceutical composition comprising bacteria and/or microbial extracellular vesicles (mEVs), the method comprising performing an assay to detect the presence of an animal hemoglobin in the pharmaceutical composition.
Dependencies are inferred from the claim text.