Multi-modal microscopic imaging
AssigneeInscopix, Inc.
InventorsKoen VISSCHER, Pei Sabrina XU, Shay NEUFELD
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Abstract
An adapter configured to be optically coupled to a plurality of microscopes and having (i) a first microscope interface configured to optically couple a first microscope system to an optical element that is in optical communication with an optical probe to provide first imaging data of a sample, and (ii) a second microscope interface configured to optically couple a second microscope system to the optical element to provide second imaging data of the sample. An optical imaging apparatus and method utilizing such adapter.
Claims32
An optical imaging apparatus configured to carry out multi-modal imaging of an internal tissue within a subject, the system comprising:
- an adapter comprising (i) a first microscope interface configured to optically couple a first microscope system to an optical element inside the adapter to provide first imaging data of a sample, and (ii) a second microscope interface configured to optically couple a second microscope system to the optical element to provide second imaging data of the sample;
- and
- an optical assembly that is coupled with the adapter at an interface of the first and second microscope interfaces and that includes:
- i. a portion of an illumination optical arm of a chosen microscope system of the first and second microscope systems, said portion of the illumination optical arm comprising one or more illumination light-emitting elements and configured to direct illumination light to said tissue within a specified field-of-view (FOV);
- and
- ii. a portion of a stimulation optical arm of the chosen microscope system comprising one or more stimulation light-emitting elements and configured to direct stimulation light to at least one of a first portion of said tissue within the specified FOV, a second portion of said tissue outside of the specified FOV, and to a third portion of said tissue that is partially within the specified FOV.
Dependencies are inferred from the claim text.