Screening kit and diagnosis system for primary aldosteronism

Abstract

The present invention provides a screening kit and a confirmed and typing diagnosis system for primary aldosteronism. A sample is pretreated by a magnetic bead bonded with a balanced hydrophilic-lipophilic polymer on the surface thereof, and process conditions are optimized and the content of each the six markers such as, aldosterone in the sample is accurately detected by liquid chromatography-tandem mass spectrometry for one time, thus finding the optimal screening cut-off value of 20.4; when a positive result is judged, PA is confirmed and subjected to typing diagnosis according to the test values of the markers, thereby achieving the simultaneous detection of the content of each the six markers such as, aldosterone on the same platform. Therefore, the present invention is integrated with screening, confirmed and typing diagnosis functions, thus providing a reliable laboratory examination basis for clinicians to formulate an effective therapeutic regimen.

Dependencies are inferred from the claim text.