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US 2024/0109875 A1Published application
Novel method for synthesizing nca compounds
AssigneesEcole Nationale Superieure De Chimie De Montpellier (Enscm), Universite De Montpellier (Um), Centre National De La Recherche Scientifique
InventorsGuillaume LACONDE, Jean MARTINEZ, Muriel AMBLARD-CAUSSIL
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Abstract
A novel method for synthesizing NCA compounds. Also, a new use of a peptide coupling agent. The method makes it possible to obtain NCA compounds from α-amino-acids, under mild and non-racemic reaction conditions, and in the absence of constraining reagents of use, such as phosgene, which may lead to the formation of undesirable by-products.
Claims19
-15. (canceled)
A method for preparing of a NCA compound, comprising:
- a step of contacting a N-protected α-amino-acid compound with propane-phosphonic acid anhydride, in an organic solvent, to obtain said compound NCA.
An NCA compound, of the following structure:
Dependencies are inferred from the claim text.