System of modular kits to produce chemical targets of interest

A modular kit system for use in manufacturing chemical compositions, the modular kit system comprising:

• a. two or more fluidically connected unit operation modules each configured to perform a unit operation in chemical synthesis processes, wherein each unit operation module comprises:
• i. a chassis;
• ii. a unit operation module controller affixed in the chassis, wherein the unit operation module controller is operable to control a unit operation performed by the unit operation module in a process of manufacturing a chemical composition and wherein the unit operation controller is operable to receive sensor data and communicate with one or more controllers;
• iii. a unit operation component affixed in the chassis, wherein the unit operation component is selected from the group consisting of reactors, separators, filter washer dryers, crystallizers, formulators, evaporators, and any combination thereof;
• iv. one or more fluidic connections operable to fluidically connect two or more unit operation modules;
• and
• v. one or more ancillary components selected from vessels, temperature control devices, mixers, valves, sensors, pumps, power supplies, and any combination thereof;
• and
• b. a kit system master controller in electronic communication with each unit operation module controller, wherein the master system controller is operable to be programmed to execute a chemical synthesis process for manufacturing a chemical composition of interest;
• wherein providing the modular kit system with precursors and reagents and activation of the modular kit system synthesizes the chemical composition of interest.

A programmed kit system (pharmacy on demand;

• “PoD”) unit to produce and provide pharmaceutical precursor molecules, and/or active pharmaceutical ingredients (API) and/or finished pharmaceuticals directly to one or more subjects in need thereof, within minutes to weeks of manufacturing, the PoD unit comprising:
• a. two or more fluidically connected unit operation modules each configured to perform a unit operation in chemical synthesis processes of the PoD, wherein each unit operation module comprises:
• i. a chassis;
• a unit operation module controller affixed in the chassis, wherein the unit operation module controller is operable to control a unit operation performed by the unit operation module in a process of manufacturing a chemical composition and wherein the unit operation controller is operable to receive sensor data and communicate with one or more controllers;
• iii. a unit operation component affixed in the chassis, wherein the unit operation component is selected from the group consisting of reactors, separators, filter washer dryers, crystallizers, formulators, evaporators, and any combination thereof;
• iv. one or more fluidic connections operable to fluidically connect two or more unit operation modules;
• and
• v. one or more ancillary components selected from vessels, temperature control devices, mixers, valves, sensors, pumps, power supplies, and any combination thereof;
• and
• b. a kit system master controller in electronic communication with each unit operation module controller, wherein the master system controller is programmed to execute a chemical synthesis process for manufacturing a chemical composition of interest;
• wherein providing the PoD with precursors and reagents and activation of the modular kit system synthesizes the chemical composition of interest.

A method for making a chemical composition using the system of any one of the preceding claims, the method comprising:

• a. determining the number and type of unit operation modules necessary to synthesize a chemical composition of interest;
• b. fluidically and electronically connecting the unit operation modules of a) to each other in a predetermined sequence identified in a);
• c. programming the kit system master controller to execute the chemical synthesis process of the chemical composition of interest using the one or more of the unit operation module kits of a);
• d. adding all of the reagents and precursors to the vessels of the unit operation module kit as determined in step a);
• and
• e. activating the system to prepare the chemical composition of interest.