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US 2024/0091372 A1Published application
Anti-doppel antibody drug conjugates
AssigneesSeoul National University R&Db Foundation, Osong Medical Innovation Foundation
InventorsYoungro BYUN, Ha Kyeong LEE, Seungwoo CHUNG, Byoung Mo KIM, So-Young CHOI, Se-Ra LEE
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Abstract
Described are anti-doppel antibody-drug conjugates, compositions comprising them, and related methods of treating doppel-associated diseases and conditions, including cancer.
Claims31
An anti-doppel antibody drug conjugate (ADC), comprising:
- (i) a doppel-targeting moiety that binds to doppel, joined directly or through a linker to
- (ii) a cleavable linker, joined directly or through a linker to
- (iii) a therapeutic agent.
Dependencies are inferred from the claim text.