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US 2024/0082428 A1Published application
Genetic therapy for glaucoma and optic neuropathies
AssigneesThe Board of Trustees of the Leland Stanford Junior University, The United States Government as represented by the Department of Veterans Affairs
InventorsJeffrey L. Goldberg, Kun-Che Chang
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Abstract
Methods and compositions are provided for the treatment of glaucoma and other optic neuropathies.
Claims18
A method of treating glaucoma or other optic neuropathies, the method comprising:
- delivering to a retinal ganglion cell in the eye of a subject, a composition comprising a polynucleotide sequence that:
- (i) encodes one or both of Pou2f2 and Tppp3;
- (ii) is a fragment of one or both of Pou2f2 and Tppp3 sequences, or (iii) is complementary to one or both of Pou2f2 and Tppp3 sequences;
- thereby preventing or reducing glaucoma or other optic neuropathies.
1 more element
Dependencies are inferred from the claim text.