Back to results
US 2024/0082418 A1Published application
Method for producing antibody-drug conjugate
AssigneeDaiichi Sankyo Company, Limited
InventorsYoshio NISHI, Kohei SAKANISHI, Shigeru NOGUCHI, Tadahiro TAKEDA
Life of this patent
Estimating the term…
Abstract
A method for producing a compound represented by formula (C) wherein R1 represents an amino group protected with a protecting group, the method comprising a step of subjecting a compound represented by formula (B) wherein R1 represents the same meaning as above, to intramolecular cyclization to convert the compound into the compound represented by formula (C).
Claims13
A method for producing a compound represented by formula (E):
- wherein R1 represents an amino group protected with a protecting group, the method comprising a step of coupling a compound represented by formula (D):
- wherein X represents a leaving group, and R1 represents the same meaning as above, with 3-butenoic acid to convert the compound represented by formula (D) into the compound represented by formula (E).
Dependencies are inferred from the claim text.