Delivery system for use in medicine
AssigneeSintef Tto AS
InventorsYrr Mørch, Einar Sulheim
Life of this patent
Estimating the term…
Abstract
The present invention relates generally to pharmaceutical formulations. Particularly, the present invention relates to a new delivery system for delivery of medical components to the lungs, and its utility in the fields of pharmaceutical formulation, drug delivery, medicine and diagnosis.
Claims19
-23. (canceled)
A delivery system comprising a gas-filled microbubble, a plurality of nanoparticles and at least one medical component associated
- with one or more of the nanoparticle for delivery of the medical component
- to a target tissue being a lung, tissue of a respiratory system and/or a nearby tissue, wherein the delivery system is administered into the bloodstream, and the delivery of the nanoparticles and the medical component to the target tissue is without focused ultrasound, wherein the medical component is a chemotherapeutic.
A method for preparing a drug delivery system comprising the steps of:
- a. Synthesizing the nanoparticles to be loaded with the medical component.
- b. Adding nanoparticles to a solution comprising a surface-active compound and/or a modifying agent.
- c. Adding gas to the solution
- d. Mixing the solution to obtain gas-filled microbubbles.
A method of delivering at least one medical component associated with a nanoparticle to a target tissue that is a lung, tissue of a respiratory system and/or a nearby tissue and releasing the medical component into the target tissue, the method comprising intravenously administering a delivery system into the bloodstream, wherein the delivery system comprises a gas-filled microbubble, a plurality of nanoparticles and at least one medical component associated with one or more of the nanoparticles, wherein the medical component is an antibiotic and wherein the delivery to the target tissue and the release of the medical component is without ultrasound.
A method of delivering at least one medical component associated with a nanoparticle to a target tissue that is a lung, tissue of a respiratory system and/or a nearby tissue and releasing the medical component into the target tissue, the method comprising intravenously administering a delivery system into the bloodstream, wherein the delivery system comprises a gas-filled microbubble, a plurality of nanoparticles and at least one medical component associated with one or more of the nanoparticles, wherein the medical component is an antifungal and wherein the delivery to the target tissue and the release of the medical component is without ultrasound.
Dependencies are inferred from the claim text.