Systems and methods for cell manufacturing

A method for culturing cells, comprising:

• introducing a plurality of cell colonies to a first surface of a cell culture container, the first surface being configured for a plurality of cell colonies to continuously adhere thereto throughout a cell culture process;
• capturing one or more time-series images of the plurality of cell colonies by an image sensor during a cell culture process;
• tracking, by a computing subsystem, one or more characteristics of the plurality of cell colonies based on the one or more time-series images;
• and
• controlling, by the computing subsystem, a cell removal tool to remove one or more cell colony from the first surface of the cell culture container during the cell culture process based on the one or more characteristics.

A computer program product for culturing cells, the computer program product comprising a computer readable storage medium having program instructions embodied therewith, the program instructions executable by a processor to cause the processor to perform a method comprising:

• receiving one or more time-series images of a plurality of cell colonies captured during a cell culture process, the plurality of cell colonies continuously adhered to a first surface throughout the cell culture process;
• tracking, by a computing subsystem, one or more characteristics of the plurality of cell colonies based on the one or more time-series images;
• and
• controlling, by the computing subsystem, a cell removal tool to remove one or more cell colony from a substrate during the cell culture process based on the one or more characteristics.