Amycolatopsis strains for vanillin production with suppressed vanillic acid formation

A non-GMO mutant strain of Amycolaptosis sp., comprising:

• occurring mutant strain of Amycolaptosis sp., formed by exposing a strain of Amycolaptosis sp., capable of producing vanillin and of metabolizing vanillin to vanillic acid to at least one mutagen, wherein said mutant strain of Amycolaptosis sp., is capable of producing vanillin and exhibits less degradation of vanillin to vanillic acid than does the strain, as measured by the accumulation level of vanillic acid in said mutant strain versus in the strain.

The mutant strain according to c, wherein the mutant strain of Amycolaptosis sp., is a mutant of ATCC 39116.

A strain of Amycolaptosis sp., comprising:

• a. a non-naturally occurring strain of Amycolaptosis sp., that includes a gene encoding vanillin dehydrogenase and at least one mutation in the gltBD operon, wherein said strain of Amycolaptosis sp., converts less vanillin to vanillic acid than does a strain of Amycolaptosis sp., without said at last one mutation in gltBD operon, wherein the gltBD operon incudes a gltB gene and a gltD gene.