African swine fever diva immunoassay
AssigneeIntervet Inc.
InventorsErwin Van Den Born, Urs Peter Bruderer
Life of this patent
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Abstract
The invention relates to a diagnostic use of an African Swine Fever Vims CD2v protein, a method, a device, and a kit for the detection of the presence of ASFV antibodies in a test sample, in particular the use thereof in a DIVA immunoassay.
Claims13
1-22. (canceled)
A method for determining whether a swine is infected with a wild-type ASFV or vaccinated with an accompanying ASFV live attenuated virus CD2v-marker vaccine (LAV CD2v-marker vaccine) wherein the method is an immunoassay, characterized in that an isolated antigenic fragment of a ASFV CD2v protein that is bound to a solid support is used as an antigen in the immunoassay and the method comprises a step of examining a test sample obtained from the swine for the presence of ASFV CD2v antibodies that bind to the antigen, and in that the antigen is a polypeptide comprising an antigenic fragment of the extracellular domain of the CD2v protein, wherein the antigenic fragment of the extracellular domain is a polypeptide comprising an amino acid sequence with at least 95% amino acid sequence identity to SEQ ID NO:
- 25.
Dependencies are inferred from the claim text.