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US 2024/0000978 A1Published application
Method for immune cell tracking
AssigneeMegaPro Biomedical Co., Ltd.
InventorsChih-Lung Chen, Wen-Yuan Hsieh, Chen-Hsuan Lin, Shian-Jy Wang
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Abstract
A method of tracking immune cells to detect immune response. The method including steps of identifying a patient having a disease associated with an organ; administering biocompatible magnetic nanoparticles into the blood stream of the patient; and obtaining a magnetic resonance image of the organ. The presence of hyperintense or hypointense spots in the magnetic resonance image indicates immune response in the patient.
Claims23
A method of tracking immune cells, the method comprising:
- identifying a patient having a disease associated with an organ;
- providing an aqueous suspension containing biocompatible magnetic nanoparticles, the aqueous suspension being free of particles having a size greater than 1000 nm, the biocompatible magnetic nanoparticles each containing a superparamagnetic core that is covered by one or more biocompatible polymers, each of which has a polyethylene glycol group, a silane group, and a linker linking, via a covalent bond, the polyethylene glycol group and the silane group;
- administering the aqueous suspension into the blood stream of the patient;
- and
- after the administration step, obtaining a magnetic resonance image of the organ, wherein the presence of hyperintense or hypointense spots in the magnetic resonance image indicates immune response in the patient.
2 more elements
Dependencies are inferred from the claim text.