Cancer Score for Assessment and Response Prediction from Biological Fluids
AssigneeNantOmics, LLC
InventorsShahrooz Rabizadeh, Patrick Soon-Shiong
Life of this patent
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Abstract
Methods for analyzing omics data and using the omics data to determine prognosis of a cancer, to predict an outcome of a treatment, and/or to determine an effectiveness of a treatment are presented. In preferred methods, blood from a patient having a cancer or suspected to have a cancer is obtained and blood omics data for a plurality of cancer-related, inflammation-related, or DNA repair-related genes are obtained. A cancer score can be calculated based on the omics data, which then can be used to provide a cancer prognosis, a therapeutic recommendation, an effectiveness of a treatment.
Claims17
A method of evaluating an effectiveness of a treatment for a cancer patient, comprising:
- obtaining blood from a patient having a cancer;
- obtaining from the blood omics data of the cancer patient before and after the treatment for a plurality of cancer-related genes, wherein the omics data comprise at least one of DNA sequence data, RNA sequence data, and RNA expression level;
- analyzing the omics data to generate first and second cancer gene scores, wherein the first and cancer gene scores correspond to the omics data before and after the treatment, respectively;
- and
- providing the effectiveness of the treatment based on a comparison of the first and second cancer gene scores.
Dependencies are inferred from the claim text.