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AssigneesNew York Stem Cell Foundation, Inc., Memorial Sloan Kettering Cancer Center
InventorsBjarki Johannesson, Daniela Cornacchia, Bianca Migliori, Brodie Fischbacher
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The present disclosure provides automated methods and systems for implementing an aging analysis pipeline involving the training and deployment of a predictive model for predicting cellular ages of cells. Such a predictive model distinguishes between morphological cellular phenotypes e.g., morphological cellular phenotypes elucidated using Cell Paint, exhibited by cells of different ages. The predictive model is further useful for developing new cellular aging assays that include biomarkers that heavily contribute towards predictions of the predictive model. Furthermore, the predictive model is useful for screening drug candidates for their ability to alter or suppress age related phenotypes.
1-82. (canceled)
A method comprising:
A non-transitory computer-readable medium comprising instructions that, when executed by a processor, cause the processor to:
A method comprising:
Dependencies are inferred from the claim text.