Uv coatings and dyes for laser capture microdissection
AssigneeGeorge Mason Research Foundation, Inc.
InventorsLance A. LIOTTA, Alessandra Luchini KUNKEL, Marissa Ashton HOWARD, Amanda Haymond STILL, Harini SOMANCHI, Philip Andrew PAPPALARDO
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Abstract
Laser Capture Microdissection devices and methods are provided. A Laser Capture Microdissection device contains a transmissive film and a transfer film. The transmissive film includes a first material configured to transmit laser energy. The transfer film includes a second material configured to absorb UV-laser energy. The transfer film contains an absorptive substance to absorb UV-laser energy and convert it into heat.
Claims20
A device comprising a transmissive film and a transfer film, the transmissive film comprising a first material configured to transmit a first ray comprising a first wavelength of about 280 nm to about 380 nm, and the transfer film comprising a second material configured to absorb the first ray;
- and wherein the device is configured to be a capture element.
A method comprising:
- a) placing a sample on a stage of an instrument comprising a capture element, wherein the instrument is configured to examine the sample;
- b) transmitting a UV ray through the capture element, wherein an absorptive substance in the capture element is configured to absorb the UV ray and convert into heat;
- c) capturing a portion of the sample on the capture element;
- and
- d) analyzing the sample.
A system comprising a capture element comprising a transmissive film and a transfer film, wherein the transmissive film comprising a first material configured to transmit a ray comprising a wavelength of about 300 nm to about 1100 nm, and the transfer film comprising a second material configured to absorb a first ray comprising of a wavelength of about 280 nm to 380 nm;
- wherein the second material comprises an absorptive material and wherein the system is configured to examine a sample placed on a stage of the system.
Dependencies are inferred from the claim text.