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US 2023/0416758 A1Published application
Trna fragments and methods of use
AssigneeThomas Jefferson University
InventorsYohei Kirino, Kamlesh Ganesh Pawar
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Abstract
The present invention provides fragments of tRNA molecules and methods of use thereof to modulate toll like receptor (TLR) signaling, for immunotherapy and for other therapeutic applications.
Claims24
A method of treating or preventing a disease or disorder in a subject in need thereof, the method comprising administering a nucleic acid molecule comprising a fragment or variant of a tRNA molecule to the subject.
A nucleic acid molecule comprising a fragment or variant of a tRNA molecule.
Dependencies are inferred from the claim text.