US 2023/0416718 A1 · THERMOTOLERANT PROTEIN GLUTAMINASE

Abstract

Disclosed is a protein glutaminase having improved thermotolerance. A protein glutaminase comprising a polypeptide indicated in any among (1) to (3) has improved thermotolerance. (1) A polypeptide comprising a SEQ ID NO: 1 or 2 amino acid sequence; (2) a polypeptide wherein one or more amino acid residues are substituted, added, inserted or lost in the amino acid sequence indicated by SEQ ID NO: 1 or 2 and exhibiting the same thermotolerance as the amino acid sequence indicated by SEQ ID NO: 1 or 2: and (3) a polypeptide having at least 76% sequence identity with the amino acid sequence indicated by SEQ ID NO: 1 or 2 and having similar thermotolerance to a polypeptide comprising the amino acid sequence indicated by SEQ ID NO: 1 or 2.

Claims9

Dependent claims

A protein-glutaminase comprising a polypeptide shown in any one of the following (1) to (3):

(1) a polypeptide having an amino acid sequence shown in SEQ ID NO:
1 or 2;
(2) a polypeptide having an amino acid sequence obtained by substituting, adding, inserting, or deleting one or more amino acid residues in an amino acid sequence shown in SEQ ID NO:
1 or 2, the polypeptide having thermostability equivalent to thermostability of a polypeptide having an amino acid sequence shown in SEQ ID NO:
1 or 2;
and
(3) a polypeptide having an amino acid sequence having a sequence identity to an amino acid sequence shown in SEQ ID NO:
1 or 2 of 76% or more, the polypeptide having thermostability equivalent to thermostability of a polypeptide having an amino acid sequence shown in SEQ ID NO:
1 or 2.

6 more elements

Dependencies are inferred from the claim text.

Thermotolerant protein glutaminase

Life of this patent

Thermotolerant protein glutaminase

Life of this patent

Abstract

Claims9