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US 2023/0416407 A1Published application
Fgf21 mimetic antibodies and uses thereof
AssigneeNovartis AG
InventorsRegis CEBE, Stephane OLLAND, David Langdon YOWE
Life of this patent
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Abstract
The present disclosure relates to monoclonal antibodies and antigen-binding fragments thereof that bind to human β-klotho, and pharmaceutical compositions and methods of treatment comprising the same.
Claims11
-25. (canceled)
A method of treating a metabolic disorder comprising administering to a subject afflicted with the metabolic disorder an effective amount of an antibody that binds to β-klotho, or antigen-binding fragment thereof, comprising a variable heavy chain as set forth in SEQ ID NO:
- 15, and a variable light chain as set forth in SEQ ID NO:
- 26 or 32.
Dependencies are inferred from the claim text.