Antibodies Directed Against T Cell Immunoglobulin and Mucin Protein 3 (TIM-3)
AssigneesAnaptysBio, Inc., Tesaro, Inc.
InventorsDavid J. King, Marilyn Kehry, Srimoyee Ghosh, Baochuan Huang
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Abstract
Provided herein are anti-T Cell Immunoglobulin and Mucin Protein-3 (TIM-3) antibodies having particular immunoglobulin heavy chain polypeptide and immunoglobulin light chain polypeptide sequences and methods of using the anti-TIM-3 antibodies to treat a disorder or disease that is responsive to TIM-3 inhibition, such as cancer, an infectious disease, or an autoimmune disease.
Claims39
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An antibody agent comprising a heavy chain polypeptide comprising an amino acid sequence having at least 80% sequence identity to SEQ ID NO:
- 1, and a light chain polypeptide comprising an amino acid sequence having at least 80% sequence identity to SEQ ID NO:
- 2.
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Dependencies are inferred from the claim text.