Olfactory receptors for use as targets for antigen binding molecules to detect and treat cancer
AssigneeH. Lee Moffitt Cancer Center and Research Institute, Inc.
InventorsJose CONEJO-GARCIA, Alexandra MARTIN
Life of this patent
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Abstract
Disclosed are compositions that selectively bind OR2H1, OR52R1, OR56A3, OR12D2, OR2G3, OR8B2, OR8B3, OR51F1, OR8K3, OR8B4, OR6Q1, OR5M8, and/or OR5V1 and the use of said compositions for the treatment of a cancer. Also disclosed herein are methods for detecting a cancer based on the presence or overexpression of OR2H1, OR52R1, OR56A3, OR12D2, OR2G3, OR8B2, OR8B3, OR51F1, OR8K3, OR8B4, OR6Q1, OR5M8, and/or OR5V1.
Claims33
An antigen binding molecule that selectively binds to an olfactory receptor selected from the group consisting of OR2H1, OR52R1, OR56A3, OR12D2, OR2G3, OR8B2, OR8B3, OR51F1, OR8K3, OR8B4, OR6Q1, OR5M8, and OR5V1.
33-115. (canceled)
Dependencies are inferred from the claim text.