Antigen-binding molecules and uses thereof

An antigen-binding molecule that specifically binds to interleukin-31 (IL-31), wherein the antigen-binding molecule comprises an immunoglobulin heavy chain variable domain (VH) and an immunoglobulin light chain variable domain (VL), wherein the VH comprises a complementarity determining region 1 (VH CDR1) comprising the amino acid sequence of SEQ ID NO:

• 6 or an amino acid sequence having at least 80% sequence identity thereto, a VH CDR2 comprising the amino acid sequence of SEQ ID NO:
• 7 or an amino acid sequence having at least 80% sequence identity thereto and a VH CDR3 comprising the amino acid sequence of SEQ ID NO:
• 8 or an amino acid sequence having at least 80% sequence identity thereto;
• and wherein the VL comprises a complementarity determining region 1 (VL CDR1) comprising the amino acid sequence of SEQ ID NO:
• 9 or an amino acid sequence having at least 80% sequence identity thereto, a VL CDR2 comprising the amino acid sequence of SEQ ID NO:
• 10 or an amino acid sequence having at least 80% sequence identity thereto, and a VL CDR3 comprising the amino acid sequence of SEQ ID NO:
• 11 or an amino acid sequence having at least 80% sequence identity thereto, wherein the amino acid sequences of the CDR are based on IMGT numbering.