Compounds, compositions, and methods for treating diseases
AssigneeDrexel University
InventorsFelix Kim, Joseph Salvino
Life of this patent
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Abstract
The present application is directed, in part, to compounds, and/or pharmaceutically acceptable salts or solvates thereof, and/or pharmaceutical compositions thereof, for modulating the activity of Sigma1 receptor. The present application is further directed, in part, to methods for treating and/or preventing cancer using compounds disclosed herein, and/or pharmaceutically acceptable salts or solvates thereof, and/or pharmaceutical compositions thereof.
Claims13
A method of treating or ameliorating cancer in a mammal, the method comprising administering to the mammal a therapeutically effective amount of a compound of Formula (I), or a pharmaceutically acceptable salt or solvate thereof:
- wherein:
- R1 is selected from the group consisting of H, halo, and haloalkyl;
- and
- R2 is pyrimidinyl.
A method of treating or ameliorating pain, the method comprising administering to the mammal a therapeutically effective amount of a compound of Formula (I), or a pharmaceutically acceptable salt or solvate thereof:
- wherein:
- R1 is selected from the group consisting of H, halo, and haloalkyl;
- and
- R2 is pyrimidinyl.
A method of treating or ameliorating a neurological disease, the method comprising administering to the mammal a therapeutically effective amount of a compound of Formula (I), or a pharmaceutically acceptable salt or solvate thereof:
- wherein:
- R1 is selected from the group consisting of H, halo, and haloalkyl;
- and
- R2 is pyrimidinyl.
Dependencies are inferred from the claim text.