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US 2023/0416204 A1Published application
Aminopyridine compound and application thereof
AssigneeMedshine Discovery Inc.
InventorsShuhui CHEN, Xiaoping ZHENG, Zhigan JIANG, Haiying HE
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Abstract
An aminopyridine compound, which is specifically a compound represented by formula (P), and a pharmaceutically acceptable salt thereof. The compound can be used to prepare drugs for treating deep fungal infections.
Claims16
A compound of formula (P) or a pharmaceutically acceptable salt thereof,
- wherein,
- ring A is selected from
- T1 and T2 are selected from CH and N;
- L1 is selected from —O—, —CH2O— and —OCH2—, and the —CH2O— and —OCH2 are optionally substituted by 1 or 2 halogens;
- each R1 is independently selected from H, F, Cl, Br, I, OH, and NH2;
- each R2 is independently selected from F, Cl, OH, NH2, and C1-3 alkyl, and the C1-3 alkyl is optionally substituted by 1, 2, or 3 Ra;
- R3 is selected from
- each R4 is independently selected from H, F, Cl, Br, and I;
- each Ra is independently selected from F, Cl, Br, and I;
- m is selected from 1, 2, 3, and 4;
- n is selected from 1, 2, 3, and 4;
- z is selected from 1, 2, and 3.
9 more elements
A compound as shown below or a pharmaceutically acceptable salt thereof, selected from
Dependencies are inferred from the claim text.