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US 2023/0414878 A1Published application
Formulations, methods, and pre-filled injection devices without fatty acid particles
AssigneeW. L. Gore & Associates, Inc.
InventorsEdward C. Gunzel, Thomas W. Patapoff
Life of this patent
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Abstract
The present disclosure is directed to pre-filled injection devices and related therapeutic formulations and methods that lack fatty acid particles. The therapeutic formulation may remain fatty acid particle free or substantially fatty acid particle free over time or when subjected to accelerated aging conditions.
Claims23
A pre-filled injection device comprising:
- a stopper;
- a barrel;
- a solid lubricant on at least one of the stopper and the barrel, the pre-filled injection device being free or substantially free of a liquid lubricant;
- and
- a therapeutic formulation having lipase activity and comprising at least about 1 mg/ml of one or more active pharmacological agents,
- wherein the therapeutic formulation is free or substantially free of fatty acid particles.
3 more elements
-98. (canceled)
Dependencies are inferred from the claim text.